Staf ’ 15
نویسندگان
چکیده
Over the past decade, cloud services emerged as one of the most promising technologies in IT. Since cloud computing allows improving the quality of software and, at the same time, aims at reducing costs of operating software and hardware, more and more software is delivered as a service in the cloud. However, moving existing software applications to the cloud and making them behave as software as a service is still a major challenge. In fact, in addition to technical aspects, business aspects also need to be considered. The ARTIST EU project (FP7) proposes a comprehensive model-based modernization approach, covering both business and technical aspects, to cloudify already existing software. In particular, ARTIST employs MDE techniques to automate the reverse engineering and forward engineering phases in a way that modernized software truly benefits from targeted cloud environments. In this paper we describe the overall ARTIST approach and present several lessons learned.
منابع مشابه
Staf, a promiscuous activator for enhanced transcription by RNA polymerases II and III.
Staf is a zinc finger protein that we recently identified as the transcriptional activator of the RNA polymerase III-transcribed selenocysteine tRNA gene. In this work we demonstrate that enhanced transcription of the majority of vertebrate snRNA and snRNA-type genes, transcribed by RNA polymerases II and III, also requires Staf. DNA binding assays and microinjection of mutant genes into Xenopu...
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STAF [Sec (selenocysteine) tRNA gene transcription activating factor] is a transcription activating factor for a number of RNA Pol III- and RNA Pol II-dependent genes including the Trsp [Sec tRNA gene], which in turn controls the expression of all selenoproteins. Here, the role of STAF in regulating expression of Sec tRNA and selenoproteins was examined. We generated transgenic mice expressing ...
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Staf is a transcriptional activator of prime importance for enhanced transcription of small nuclear (snRNA) and snRNA-type genes transcribed by RNA polymerases II and III (Pol II and III). In addition to this activity, it also possesses the capacity to stimulate expression from an RNA polymerase II mRNA promoter. This promiscuous activator thus provides a useful model system for studying the me...
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